Brendel is a surname. Notable people with the surname include:Albert Brendel (1893–1943), Knight's Cross of the Iron Cross recipient
Albert Heinrich Brendel (1827–1878), German painter
Alfred Brendel (1931–2025), Czech-born Austrian classical pianist, poet and essayist
Brian Brendell, Namibian footballer
Cornelia Brendel, birth name of Cornelia Foss
Daniela Brendel, German swimmer
El Brendel (1890–1964), American entertainer
Franz Brendel (1811–1868), 19th-century music critic and publisher
Franz Brendel (canoeist), German canoeist
Günther Brendel (1930–2026), German painter, graphic artist, and academic
Henry W. Brendel (1857–1940), American lawyer and government official
Jake Brendel, American football player
Jakob Brendel (1907–1964), German wrestler
Joachim Brendel (1921–1974), German Luftwaffe pilot
Karl Brendel (1871–1925), German sculptor
Leif Brendel (1903–1972), Norwegian editor
Maria Weigert Brendel (1902–1994), German classical art expert, wife of Otto Brendel
Martin Brendel (1862–1939), German astronomer
Neal Brendel (1954–2021), American rugby union player and lawyer
Otto Brendel (1901–1973), scholar of Etruscan art
Pascal Brendel, German artistic gymnast
Robert Brendel, German botanist and model maker
Sarah Brendel, German pop singer
Sebastian Brendel, German canoeist
Willi Brendel (1938–2006), German field hockey player
Wolfgang Brendel, German opera singer
